By Larry B. Goldstein
Society-sanctioned directions are invaluable instruments, yet having access to key info could be a daunting activity. This ebook illuminates a transparent route to profitable program of the yank middle Association/American Stroke organization guidance. prepared for quick reference, this new quantity is helping practitioners enhance sufferer care.
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Additional info for A Primer on Stroke Prevention and Treatment: An overview based on AHA/ASA Guidelines
For example, the Asia Pacific Cohort Studies Collaboration found a 25% increase in ischemic stroke rates for every 1 mmol/L increase in total cholesterol . The data on the relationship between low-density lipoprotein (LDL) cholesterol and ischemic stroke are weaker, whereas several studies have shown increased prevalence of ischemic stroke in persons with low high-density lipoprotein Chapter 3 Primordial and Primary Prevention of Stroke (HDL) cholesterol (especially less than 30 mg/dL) .
Treatment with statins shows reduction in coronary atherosclerotic plaque progression and reduction of CRP levels. Lower CRP levels after statin therapy were associated with better clinical outcomes in patients with acute coronary syndromes . It is unclear if asymptomatic patients with increased CRP levels reduce their risk of stroke with the use of statins . The vascular response to injury prompts the migration of inflammatory cells and the release of pro-inflammatory cytokines that convert the endothelial surface over a plaque to a prothrombotic state .
Atrial fibrillation AF is responsible for approximately 60,000 strokes per year in the United States, or in 2–4% of persons with AF without previous history of cerebral ischemia. It is prevalent in older patients, affecting 5% of persons older than 70 years. It is responsible for almost 25% of all strokes in patients older than 80 years . Treatment with antithrombotics reduces the odds of stroke. Warfarin is more efficacious than aspirin, leading to 45% stroke risk reduction compared with aspirin in persons with AF .